IRREVERSIBLE HEMORRHAGIC SHOCK IN GERMFREE RATS
نویسندگان
چکیده
منابع مشابه
Irreversible Hemorrhagic Shock in Germfree Rats
Evidence has been provided that a state of irreversible hemorrhagic shock can be induced in a bacteria-free environment in rats reared under germfree conditions. The response to bleeding, the duration of the hypotensive episode and the pathological changes were the same in the germfree and in normal stock rats. The findings are interpreted as evidence opposed to the concept that bacteria or bac...
متن کاملHemorrhagic shock of germfree rats’
MCNULTY, Mr. P., JR. AND RAFAEL LINARES. Hemorrhagic shock ofgermfree rats. Am. J. Physiol. Ig8( I) : 141-144. 1g6o.Germfree and ordinarv laboratory rats of the same strain, half of each sort treated with oral aureomycin for 3 days prior to shock, were subjected to hemorrhagic shock. At the level and duration of hypotension selected, the procedure was highly lethal for all four groups. The sing...
متن کاملEffect of hypothermia in irreversible hemorrhagic shock.
Irreversible hemorrhagic shock was studied in normothermic dogs and in dogs subjected to hypothermia at three different periods following the onset of the hemorrhage. A significant prolongation of life was observed in the hypothermic dogs, the increase in survival time being greatest in those dogs cooled early in the shock sequence. The temperature, pulse, respiration, blood pressure, electroca...
متن کاملthe myocardial factor in irreversible hemorrhagic shock: alterations of myocardial performance of the isolated canineheart preparation following irreversible hemorrhagic shock
myocardial performance, utilizing the isolated canine heart preparation, was studied in two groups: normal control dogs and those subjected to hemorrhagic shock. a marked deterioration in myocardial functional capacity was observed in the shock group. from this study, myocardial incapacity resulting from the period of acute hypotension is felt to be a contributing factor in the death of animals...
متن کاملGranulocytes and no-reflow phenomenon in irreversible hemorrhagic shock.
Recent evidence shows that circulating granulocytes play an important role in capillary stasis and tissue injury. We investigated two aspects of the problem in a Wiggers hemorrhagic shock model of the rat: the survival rate and the microvascular no-reflow phenomenon. A conventional group of rats with normal blood cells and a neutropenic group of rats pretreated with intraperitoneal antigranuloc...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1958
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.107.3.437